Far2 | fatty acyl CoA reductase 2

GeneMGI:2687035Synonyms: Mlstd1

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Vision/eye Cardiovascular system

12 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal coat appearance6 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult7.36x10-15 
increased fasting circulating glucose level1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult4.66x10-12 
decreased circulating cholesterol level2 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult9.38x10-11 
decreased circulating HDL cholesterol level2 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult2.16x10-7 
increased heart weight1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult3.52x10-11 
abnormal lens morphology1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult1.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Far2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Far2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Far2tm2b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter