Far2 | fatty acyl CoA reductase 2

GeneMGI:2687035Synonyms: Mlstd1

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Vision/eye Cardiovascular system

12 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal coat appearance6 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult7.36x10-15 
increased fasting circulating glucose level1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult4.66x10-12 
decreased circulating cholesterol level2 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult9.38x10-11 
decreased circulating HDL cholesterol level2 supporting datasetsFar2tm2b(KOMP)WtsihomozygoteEarly adult2.16x10-7 
increased heart weight1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult3.52x10-11 
abnormal lens morphology1 supporting datasetFar2tm2b(KOMP)WtsihomozygoteEarly adult1.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Far2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Far2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Far2tm2b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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