Leprot | leptin receptor overlapping transcript

GeneMGI:2687005Synonyms: OB-RGRP, Obrgrp, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	2 supporting datasets	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	6.38x10^-7
increased bone mineral content	2 supporting datasets	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.37x10^-7
increased lean body mass	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.67x10^-9
increased food intake	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.15x10^-6
increased red blood cell distribution width	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	5.84x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Leprot.

Associated images

Loading...

Histopathology

There is no histopathology data found for Leprot.

IMPC related publications

Loading...

External links

No external links available for Leprot.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Leprot^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Leprot^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Leprot^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Leprot^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Leprot^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes