Leprot | leptin receptor overlapping transcript
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased total body fat amount | 2 supporting datasets | Leprottm2a(KOMP)Wtsi | homozygote | Early adult | 6.38x10-7 | ||
| increased bone mineral content | 2 supporting datasets | Leprottm2a(KOMP)Wtsi | homozygote | Early adult | 2.37x10-7 | ||
| increased lean body mass | 1 supporting dataset | Leprottm2a(KOMP)Wtsi | homozygote | Early adult | 1.67x10-9 | ||
| increased food intake | 1 supporting dataset | Leprottm2a(KOMP)Wtsi | homozygote | Early adult | 2.15x10-6 | ||
| increased red blood cell distribution width | 1 supporting dataset | Leprottm2a(KOMP)Wtsi | homozygote | Early adult | 5.84x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/4) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/4) | 0.19% (1/533) |
| blood vessel | heterozygote | n/a | 0% (0/4) | 0% (0/173) |
| bone | heterozygote | n/a | 0% (0/4) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/4) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/4) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/4) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/4) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/4) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/4) | 0.41% (2/491) |
External links
No external links available for Leprot.
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| Leprottm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Leprottm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Leprottm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Leprottm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Leprottm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |