Leprot | leptin receptor overlapping transcript

GeneMGI:2687005Synonyms: OB-RGRP, Obrgrp, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	2 supporting datasets	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	6.38x10^-7
increased bone mineral content	2 supporting datasets	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.37x10^-7
increased lean body mass	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.67x10^-9
increased food intake	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.15x10^-6
increased red blood cell distribution width	1 supporting dataset	Leprot^{tm2a(KOMP)Wtsi}	homozygote	Early adult	5.84x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Leprot.

Associated images

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Histopathology

There is no histopathology data found for Leprot.

IMPC related publications

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External links

No external links available for Leprot.

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*Leprot^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Leprot^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Leprot^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Leprot^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Leprot^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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