Iglon5 | IgLON family member 5
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| small kidney | 2 supporting datasets | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 2 supporting datasets | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Iglon5em1(IMPC)Mbp | homozygote | Late adult | N/A * |
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Human diseases caused by Iglon5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Iglon5.
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| Iglon5em1(IMPC)Mbp | Exon Deletion | | mouse |
| Iglon5tm365241(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |