Foxr1 | forkhead box R1

GeneMGI:2685961Synonyms: Foxn5, LOC382074

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged urinary bladder1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteLate adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFoxr1em1(IMPC)TcphomozygoteEarly adultN/A * 
small spleen1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteLate adultN/A * 
enlarged lymph nodes1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsFoxr1em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetFoxr1em1(IMPC)TcphomozygoteEarly adultN/A * 
small ovary1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteLate adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetFoxr1em1(IMPC)TcpheterozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Foxr1em1(IMPC)TcpExon Deletionmouse
Foxr1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Foxr1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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