Ccdc180 | coiled-coil domain containing 180

GeneMGI:2685871Synonyms: E230008N13Rik, LOC381522

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Reproductive system Vision/eye

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

female infertility1 supporting datasetCcdc180tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased cornea thickness1 supporting datasetCcdc180tm1b(KOMP)WtsiheterozygoteEarly adult1.13x10-7 
male infertility1 supporting datasetCcdc180tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoteWholemount images
100% (2/2)0.86% (5/579)
brainstemheterozygoten/a0% (0/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cecumheterozygoten/a0% (0/1)7.75% (22/284)
cerebellumheterozygoteWholemount images
100% (2/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
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Histopathology

IMPC related publications

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Ccdc180tm102600(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Ccdc180tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ccdc180tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ccdc180tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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