Pate2 | prostate and testis expressed 2

GeneMGI:2685692Synonyms: mANLP1, LOC330921

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Growth/size/body region Cardiovascular system

19 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology1 supporting datasetPate2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetPate2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/4)0.7% (4/570)
aortaheterozygoten/a0% (0/4)0.19% (1/533)
bloodheterozygoten/a0% (0/2)0% (0/17)
bone marrowheterozygoten/a0% (0/2)0% (0/22)
brainheterozygoten/a0% (0/4)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/4)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoten/a50% (2/4)7.75% (22/284)
cerebellumheterozygoten/a0% (0/4)0.56% (3/532)
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Histopathology

IMPC related publications

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Pate2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Pate2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Pate2tm450414(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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