Thsd7a | thrombospondin, type I, domain containing 7A

GeneMGI:2685683Synonyms: LOC330267

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal retina morphology	1 supporting dataset	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Late adult	8.5x10^-7
hyperactivity	7 supporting datasets	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Late adult	1.01x10^-14
cataract	1 supporting dataset	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Late adult	3.53x10^-5
decreased lean body mass	1 supporting dataset	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.45x10^-6
decreased bone mineral content	1 supporting dataset	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Early adult	5.97x10^-5
abnormal lens morphology	1 supporting dataset	Thsd7a^{tm1b(KOMP)Mbp}	homozygote	Late adult	1.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Thsd7a.

Associated images

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Histopathology

There is no histopathology data found for Thsd7a.

IMPC related publications

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External links

No external links available for Thsd7a.

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*Thsd7a^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Thsd7a^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Thsd7a^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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