Nup62cl | nucleoporin 62 C-terminal like
Physiological systems
16 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Vision/eye Hematopoietic system
11 No significant impact
8 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating bilirubin level | 1 supporting dataset | Nup62clem1(IMPC)J | hemizygote | Early adult | 2.89x10-15 | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Nup62clem1(IMPC)J | hemizygote | Early adult | 3.57x10-8 | ||
| increased leukocyte cell number | 1 supporting dataset | Nup62clem1(IMPC)J | hemizygote | Early adult | 1.53x10-8 | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Nup62clem1(IMPC)J | homozygote | Early adult | 3.34x10-5 | ||
| female infertility | 1 supporting dataset | Nup62clem1(IMPC)J | homozygote | Early adult | N/A * | ||
| cornea opacity | 1 supporting dataset | Nup62clem1(IMPC)J | hemizygote | Early adult | 2.89x10-5 | ||
| decreased circulating phosphate level | 1 supporting dataset | Nup62clem1(IMPC)J | hemizygote | Early adult | 1.1x10-5 |
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Human diseases caused by Nup62cl mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Nup62cl.
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| Nup62clem1(IMPC)J | Exon Deletion | | mouse |
| Nup62cltm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Nup62cltm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nup62cltm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |