Nup62cl | nucleoporin 62 C-terminal like

GeneMGI:2685565Synonyms: LOC279706

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Vision/eye Hematopoietic system

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating bilirubin level1 supporting datasetNup62clem1(IMPC)JhemizygoteEarly adult2.89x10-15 
decreased circulating aspartate transaminase level1 supporting datasetNup62clem1(IMPC)JhemizygoteEarly adult3.57x10-8 
increased leukocyte cell number1 supporting datasetNup62clem1(IMPC)JhemizygoteEarly adult1.53x10-8 
decreased circulating aspartate transaminase level1 supporting datasetNup62clem1(IMPC)JhomozygoteEarly adult3.34x10-5 
female infertility1 supporting datasetNup62clem1(IMPC)JhomozygoteEarly adultN/A * 
cornea opacity1 supporting datasetNup62clem1(IMPC)JhemizygoteEarly adult2.89x10-5 
decreased circulating phosphate level1 supporting datasetNup62clem1(IMPC)JhemizygoteEarly adult1.1x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nup62clem1(IMPC)JExon Deletionmouse
Nup62cltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Nup62cltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nup62cltm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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