Wdtc1 | WD and tetratricopeptide repeats 1

GeneMGI:2685541Synonyms: adp, adipose, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vertebral arch morphology	1 supporting dataset	Wdtc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.87x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Wdtc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.48x10^-5
decreased circulating LDL cholesterol level	1 supporting dataset	Wdtc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.62x10^-5
decreased fasting circulating glucose level	1 supporting dataset	Wdtc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.04x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wdtc1.

Associated images

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Histopathology

There is no histopathology data found for Wdtc1.

IMPC related publications

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External links

No external links available for Wdtc1.

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*Wdtc1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Wdtc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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