Nuggc | nuclear GTPase, germinal center associated

GeneMGI:2685446Synonyms: Gm600, LOC239151, +1 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Muscle Hematopoietic system Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal thymus morphology	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal digit morphology	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.99x10^-8
abnormal skeletal muscle morphology	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Nuggc^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nuggc.

Associated images

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Histopathology

There is no histopathology data found for Nuggc.

IMPC related publications

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External links

No external links available for Nuggc.

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*Nuggc^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Nuggc^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Nuggc^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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