Carmil2 | capping protein regulator and myosin 1 linker 2

GeneMGI:2685431Synonyms: Rltpr, D130029J02Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating glucose level1 supporting datasetCarmil2tm1b(KOMP)MbphomozygoteEarly adult2.54x10-5 
abnormal coat/hair pigmentation3 supporting datasetsCarmil2tm1b(KOMP)MbphomozygoteEarly adult1.63x10-11 
abnormal cholesterol homeostasis1 supporting datasetCarmil2tm1b(KOMP)MbphomozygoteEarly adult4.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Carmil2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Carmil2tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Carmil2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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