Bcl2l15 | BCLl2-like 15

GeneMGI:2685412Synonyms: LOC229672, Bfk

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.25x10^-9
increased circulating total protein level	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.42x10^-5
decreased hemoglobin content	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.01x10^-5
enlarged heart	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.65x10^-10
abnormal liver morphology	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.13x10^-5
decreased exploration in new environment	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.81x10^-7
increased startle reflex	1 supporting dataset	Bcl2l15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bcl2l15.

Associated images

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Histopathology

There is no histopathology data found for Bcl2l15.

IMPC related publications

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External links

No external links available for Bcl2l15.

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*Bcl2l15^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bcl2l15^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bcl2l15^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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