Rundc3b | RUN domain containing 3B
Physiological systems
9 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Behavior/neurological
7 No significant impact
15 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal eye anterior chamber depth | 1 supporting dataset | Rundc3bem1(IMPC)Bay | homozygote | Early adult | 3.04x10-6 | ||
| hyperactivity | 3 supporting datasets | Rundc3bem1(IMPC)Bay | homozygote | Early adult | 2.62x10-5 | ||
| decreased total retina thickness | 1 supporting dataset | Rundc3bem1(IMPC)Bay | homozygote | Early adult | 3.05x10-6 | ||
| increased vertical activity | 1 supporting dataset | Rundc3bem1(IMPC)Bay | homozygote | Early adult | 1.67x10-5 |
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Human diseases caused by Rundc3b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rundc3b.
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| Rundc3bem1(IMPC)Bay | Exon Deletion | | mouse |
| Rundc3btm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rundc3btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rundc3btm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
| Rundc3btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |