Setdb2 | SET domain, bifurcated 2

GeneMGI:2685139Synonyms: KMT1F, LOC239122

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal gait	1 supporting dataset	Setdb2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.58x10^-5
increased grip strength	4 supporting datasets	Setdb2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.58x10^-9
thrombocytopenia	1 supporting dataset	Setdb2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.98x10^-9
increased startle reflex	1 supporting dataset	Setdb2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setdb2.

Associated images

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Histopathology

There is no histopathology data found for Setdb2.

IMPC related publications

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External links

No external links available for Setdb2.

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*Setdb2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Setdb2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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