Dytn | dystrotelin

GeneMGI:2685061Synonyms: LOC241073

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult2.25x10-7 
increased exploration in new environment1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult1.4x10-6 
decreased circulating phosphate level1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult7.22x10-5 
decreased heart rate1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult9.91x10-5 
decreased heart weight1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult2.61x10-6 
increased leukocyte cell number1 supporting datasetDytnem1(IMPC)JhomozygoteEarly adult9.31x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dytnem1(IMPC)JExon Deletionmouse
Dytntm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dytntm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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