Cenpj | centromere protein J

GeneMGI:2684927Synonyms: 4932437H03Rik, Sas4

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Limbs/digits/tail Behavior/neurological Skeleton Craniofacial

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

4Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal tail movements	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.58x10^-9
abnormal behavior	10 supporting datasets	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.41x10^-16
increased total body fat amount	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.36x10^-5
decreased body weight	5 supporting datasets	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.06x10^-24
abnormal vertebrae morphology	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.4x10^-8
abnormal joint morphology	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.64x10^-14
abnormal external female genitalia morphology	2 supporting datasets	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.66x10^-15
abnormal cranium morphology	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.46x10^-11
abnormal ulna morphology	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.81x10^-9
abnormal head morphology	1 supporting dataset	Cenpj^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.18x10^-14

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cenpj.

Associated images

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Histopathology

There is no histopathology data found for Cenpj.

IMPC related publications

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External links

No external links available for Cenpj.

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*Cenpj^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cenpj^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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