Cenpj | centromere protein J

GeneMGI:2684927Synonyms: 4932437H03Rik, Sas4

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Limbs/digits/tail Behavior/neurological Skeleton Craniofacial

11 No significant impact

5 Not tested

Gene metrics:20Significant phenotypes
4Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal tail movements1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult3.58x10-9 
abnormal behavior10 supporting datasetsCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult8.41x10-16 
increased total body fat amount1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult7.36x10-5 
decreased body weight5 supporting datasetsCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult5.06x10-24 
abnormal vertebrae morphology1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult1.4x10-8 
abnormal joint morphology1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult1.64x10-14 
abnormal external female genitalia morphology2 supporting datasetsCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult1.66x10-15 
abnormal cranium morphology1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult1.46x10-11 
abnormal ulna morphology1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult6.81x10-9 
abnormal head morphology1 supporting datasetCenpjtm1a(EUCOMM)WtsihomozygoteEarly adult2.18x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cenpjtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Cenpjtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse

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