Eddm3b | epididymal protein 3B

GeneMGI:2684921Synonyms: Fam12

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Immune system Vision/eye Hematopoietic system Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased basophil cell number2 supporting datasetsEddm3btm1b(KOMP)WtsihomozygoteEarly adult4.01x10-12 
increased eosinophil cell number1 supporting datasetEddm3btm1b(KOMP)WtsihomozygoteEarly adult1.01x10-5 
dilated heart left ventricle1 supporting datasetEddm3btm1b(KOMP)WtsihomozygoteEarly adult6.15x10-5 
abnormal iris pigmentation1 supporting datasetEddm3btm1b(KOMP)WtsihomozygoteEarly adult3.54x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eddm3btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Eddm3btm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Eddm3btm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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