Vcpkmt | valosin containing protein lysine (K) methyltransferase

GeneMGI:2684917Synonyms: Mettl21d, Gm71, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Cardiovascular system

14 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased heart weight1 supporting datasetVcpkmttm1.1(KOMP)VlcghomozygoteEarly adult9.26x10-7 
increased circulating bilirubin level1 supporting datasetVcpkmttm1.1(KOMP)VlcghomozygoteEarly adult8.46x10-6 
abnormal coat appearance1 supporting datasetVcpkmttm1.1(KOMP)VlcghomozygoteEarly adult4.86x10-5 
decreased circulating glucose level1 supporting datasetVcpkmttm1.1(KOMP)VlcghomozygoteEarly adult1.87x10-6 
abnormal cholesterol homeostasis1 supporting datasetVcpkmttm1.1(KOMP)VlcghomozygoteEarly adult3.55x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vcpkmttm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Vcpkmttm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Vcpkmttm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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