Togaram1 | TOG array regulator of axonemal microtubules 1
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Cardiovascular system Mortality/aging Craniofacial
12 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
anophthalmia | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
abnormal forebrain morphology | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
microphthalmia | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
abnormal craniofacial morphology | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
abnormal limb bud morphology | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
polydactyly | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
facial cleft | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
prenatal lethality prior to heart atrial septation | 1 supporting dataset | Togaram1em1(IMPC)J | homozygote | E15.5 | N/A * |
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External links
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Togaram1em1(IMPC)J | Exon Deletion | | mouse |
Togaram1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Togaram1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |