Zbed4 | zinc finger, BED type containing 4

GeneMGI:2682302Synonyms: 1700009F06Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological Cardiovascular system Mortality/aging Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetZbed4tm1.1(KOMP)MbpheterozygoteEarly adult5.2x10-7 
preweaning lethality, incomplete penetrance3 supporting datasetsZbed4tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetZbed4tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetZbed4tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetZbed4tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetZbed4tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zbed4tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Zbed4tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Zbed4tm462883(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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