Ift172 | intraflagellar transport 172

GeneMGI:2682064Synonyms: wim, 4930553F24Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Mortality/aging Craniofacial Cardiovascular system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

7Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal allantois morphology	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal embryo development	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal digit morphology	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	3.78x10^-5
embryonic growth retardation	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
hemorrhage	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
edema	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Ift172^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ift172.

Associated images

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Histopathology

There is no histopathology data found for Ift172.

IMPC related publications

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External links

No external links available for Ift172.

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*Ift172^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ift172^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ift172^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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