Mpv17l2 | MPV17 mitochondrial membrane protein-like 2
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Pigmentation Immune system Integument Adipose tissue Growth/size/body region Nervous system Hematopoietic system
14 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:74Adult tissues
0Embryo tissues
| abnormal coat/hair pigmentation | 3 supporting datasets | Mpv17l2tm1.1(KOMP)Mbp | homozygote | Early adult | 5.27x10-13 | ||
| abnormal coat/hair pigmentation | 3 supporting datasets | Mpv17l2tm1.1(KOMP)Mbp | heterozygote | Early adult | 4.3x10-7 | ||
| abnormal spleen morphology | 1 supporting dataset | Mpv17l2tm1.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Mpv17l2tm1.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| increased total body fat amount | 2 supporting datasets | Mpv17l2tm1.1(KOMP)Mbp | homozygote | Early adult | 5.02x10-5 | ||
| hydrocephaly | 1 supporting dataset | Mpv17l2tm1.1(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Mpv17l2tm1.1(KOMP)Mbp | homozygote | Early adult | 9.46x10-5 |
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External links
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| Mpv17l2tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Mpv17l2tm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Mpv17l2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |