Aars2 | alanyl-tRNA synthetase 2, mitochondrial
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased basophil cell number | 2 supporting datasets | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 2.05x10-7 | ||
| increased eosinophil cell number | 2 supporting datasets | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 2.54x10-14 | ||
| abnormal heart left ventricle morphology | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 3.79x10-7 | ||
| increased neutrophil cell number | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 1.87x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased red blood cell distribution width | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 9.38x10-6 | ||
| abnormal vocalization | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 1.2x10-5 | ||
| impaired pupillary reflex | 1 supporting dataset | Aars2tm1(KOMP)Wtsi | heterozygote | Early adult | 7.74x10-5 |
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External links
No external links available for Aars2.
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| Aars2tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |