Skic3 | SKI3 subunit of superkiller complex
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
13 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Skic3em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased circulating potassium level | 1 supporting dataset | Skic3em1(IMPC)Tcp | heterozygote | Early adult | 1.5x10-5 | ||
| enlarged urinary bladder | 1 supporting dataset | Skic3em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Skic3em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| increased freezing behavior | 1 supporting dataset | Skic3em1(IMPC)Tcp | heterozygote | Early adult | 2.17x10-6 | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Skic3em1(IMPC)Tcp | heterozygote | Early adult | 2.43x10-5 |
| | | | | | | | | | |
External links
No external links available for Skic3.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Skic3em1(IMPC)Tcp | Exon Deletion | | mouse |