Slitrk1 | SLIT and NTRK-like family, member 1

GeneMGI:2679446Synonyms: 3200001I04Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological

17 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

small testis1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adult1.57x10-5 
improved glucose tolerance1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adult2.24x10-6 
abnormal epididymis morphology1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adult4.57x10-7 
enlarged epididymis1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
limb grasping1 supporting datasetSlitrk1tm1.1(KOMP)VlcghomozygoteEarly adult7.94x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slitrk1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Slitrk1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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