Slc24a5 | solute carrier family 24, member 5

GeneMGI:2677271Synonyms: NCX5, NCKX5, +2 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Vision/eye Behavior/neurological

12 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

abnormal coat/hair pigmentation7 supporting datasetsSlc24a5tm1b(KOMP)MbphomozygoteEarly adult4.27x10-8 
decreased fasting circulating glucose level1 supporting datasetSlc24a5tm1b(KOMP)MbphomozygoteEarly adult1.76x10-9 
impaired righting response1 supporting datasetSlc24a5tm1b(KOMP)MbphomozygoteEarly adult2.14x10-7 
abnormal iris transillumination1 supporting datasetSlc24a5tm1b(KOMP)MbphomozygoteEarly adult1.97x10-16 
increased grip strength2 supporting datasetsSlc24a5tm1b(KOMP)MbphomozygoteEarly adult4.03x10-5 
increased circulating sodium level1 supporting datasetSlc24a5tm1b(KOMP)MbphomozygoteEarly adult3.52x10-8 
abnormal retina morphology1 supporting datasetSlc24a5tm1b(KOMP)MbphomozygoteEarly adult4.19x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc24a5tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc24a5tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Slc24a5tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Slc24a5tm43958(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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