Defb14 | defensin beta 14

GeneMGI:2675345Synonyms: mBD14

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral density	1 supporting dataset	Defb14^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.62x10^-5
increased grip strength	1 supporting dataset	Defb14^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.41x10^-5
increased bone mineral content	1 supporting dataset	Defb14^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.62x10^-5
increased mean platelet volume	1 supporting dataset	Defb14^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.06x10^-5
decreased circulating glycerol level	1 supporting dataset	Defb14^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.63x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Defb14.

Associated images

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Histopathology

There is no histopathology data found for Defb14.

IMPC related publications

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External links

No external links available for Defb14.

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*Defb14^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Defb14^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Defb14^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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