Kntc1 | kinetochore associated 1

GeneMGI:2673709Synonyms: jgl

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



narrow eye opening	1 supporting dataset	Kntc1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.97x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Kntc1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Kntc1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kntc1.

Associated images

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Histopathology

There is no histopathology data found for Kntc1.

IMPC related publications

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External links

No external links available for Kntc1.

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*Kntc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Kntc1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Kntc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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