Kics2 | KICSTOR subunit 2

GeneMGI:2670984Synonyms: BC048403

Physiological systems

15 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

14 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating cholesterol level1 supporting datasetKics2tm1b(KOMP)WtsihomozygoteEarly adult1.32x10-6 
decreased circulating HDL cholesterol level1 supporting datasetKics2tm1b(KOMP)WtsihomozygoteEarly adult2.1x10-8 
decreased circulating phosphate level1 supporting datasetKics2tm1b(KOMP)WtsihomozygoteEarly adult6.56x10-8 
increased blood urea nitrogen level1 supporting datasetKics2tm1b(KOMP)WtsihomozygoteEarly adult3.15x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kics2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Kics2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Kics2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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