D630045J12Rik | RIKEN cDNA D630045J12 gene

GeneMGI:2669829

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	6 supporting datasets	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.9x10^-7
enlarged lymph nodes	1 supporting dataset	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
improved glucose tolerance	2 supporting datasets	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.61x10^-12
decreased circulating triglyceride level	1 supporting dataset	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.5x10^-5
decreased total body fat amount	2 supporting datasets	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.6x10^-5
decreased exploration in new environment	1 supporting dataset	D630045J12Rik^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.81x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for D630045J12Rik.

Associated images

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Histopathology

There is no histopathology data found for D630045J12Rik.

IMPC related publications

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External links

No external links available for D630045J12Rik.

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*D630045J12Rik^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*D630045J12Rik^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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