D630045J12Rik | RIKEN cDNA D630045J12 gene
GeneMGI:2669829
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Behavior/neurological
13 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased locomotor activity | 6 supporting datasets | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | 4.9x10-7 | ||
| enlarged lymph nodes | 1 supporting dataset | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| improved glucose tolerance | 2 supporting datasets | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | 1.61x10-12 | ||
| decreased circulating triglyceride level | 1 supporting dataset | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | 5.5x10-5 | ||
| decreased total body fat amount | 2 supporting datasets | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | 2.6x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | D630045J12Riktm1b(KOMP)Wtsi | homozygote | Early adult | 1.81x10-5 |
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Human diseases caused by D630045J12Rik mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for D630045J12Rik.
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| D630045J12Riktm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| D630045J12Riktm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |