Nutm1 | NUT midline carcinoma, family member 1

GeneMGI:2661384Synonyms: Nut, BC125332

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Hematopoietic system

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetNutm1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased circulating serum albumin level1 supporting datasetNutm1tm1b(KOMP)WtsihomozygoteEarly adult1.55x10-6 
increased lean body mass2 supporting datasetsNutm1tm1b(KOMP)WtsihomozygoteEarly adult3.35x10-8 
increased mean corpuscular hemoglobin1 supporting datasetNutm1tm1b(KOMP)WtsihomozygoteEarly adult1.42x10-6 
decreased total body fat amount1 supporting datasetNutm1tm1b(KOMP)WtsihomozygoteEarly adult2.5x10-6 
increased red blood cell distribution width1 supporting datasetNutm1tm1b(KOMP)WtsihomozygoteEarly adult1.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nutm1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Nutm1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Nutm1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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