Acvr1c | activin A receptor, type IC

GeneMGI:2661081Synonyms: Alk-7, ALK7

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Behavior/neurological Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	1 supporting dataset	Acvr1c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.34x10^-5
decreased total body fat amount	1 supporting dataset	Acvr1c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.78x10^-5
increased heart weight	1 supporting dataset	Acvr1c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.9x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acvr1c.

Associated images

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Histopathology

There is no histopathology data found for Acvr1c.

IMPC related publications

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External links

No external links available for Acvr1c.

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*Acvr1c^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Acvr1c^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Acvr1c^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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