C1rl | complement component 1, r subcomponent-like

GeneMGI:2660692Synonyms: C1rl1, C1r-LP

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Skeleton

17 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

abnormal joint morphology1 supporting datasetC1rltm1b(EUCOMM)HmguhomozygoteEarly adult6.42x10-5 
abnormal pelvic girdle bone morphology1 supporting datasetC1rltm1b(EUCOMM)HmguhomozygoteEarly adult5.45x10-5 
abnormal tibia morphology1 supporting datasetC1rltm1b(EUCOMM)HmguhomozygoteEarly adult1.07x10-5 
decreased lean body mass1 supporting datasetC1rltm1b(EUCOMM)HmguhomozygoteEarly adult7.02x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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C1rltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
C1rltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
C1rltm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
C1rltm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
C1rltm43729(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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