Gpbar1 | G protein-coupled bile acid receptor 1
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Renal/urinary system
16 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| abnormal lymph node morphology | 1 supporting dataset | Gpbar1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Gpbar1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Gpbar1tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.85x10-16 | ||
| small testis | 1 supporting dataset | Gpbar1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Gpbar1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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External links
No external links available for Gpbar1.
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| Gpbar1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Gpbar1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Gpbar1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gpbar1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |