Adam32 | a disintegrin and metallopeptidase domain 32

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased total body fat amount2 supporting datasetsAdam32tm1b(KOMP)WtsihomozygoteEarly adult2.69x10-9 
impaired pupillary reflex1 supporting datasetAdam32tm1b(KOMP)WtsihomozygoteEarly adult4.04x10-6 
decreased bone mineral content2 supporting datasetsAdam32tm1b(KOMP)WtsihomozygoteEarly adult1.77x10-7 
decreased lean body mass2 supporting datasetsAdam32tm1b(KOMP)WtsihomozygoteEarly adult1.13x10-11 
decreased bone mineral density1 supporting datasetAdam32tm1b(KOMP)WtsihomozygoteEarly adult1.28x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adam32tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Adam32tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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