Setd1b | SET domain containing 1B

GeneMGI:2652820Synonyms: KMT2G

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating HDL cholesterol level	1 supporting dataset	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	1.69x10^-5
decreased circulating triglyceride level	1 supporting dataset	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	9.1x10^-5
increased bone mineral density	1 supporting dataset	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	2.79x10^-6
increased lean body mass	2 supporting datasets	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	5.6x10^-15
decreased total body fat amount	2 supporting datasets	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	1.03x10^-13
decreased circulating cholesterol level	1 supporting dataset	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	1.17x10^-5
decreased circulating amylase level	1 supporting dataset	Setd1b^{tm1.2(IMPC)Wtsi}	heterozygote	Early adult	3.35x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setd1b.

Associated images

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Histopathology

There is no histopathology data found for Setd1b.

IMPC related publications

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External links

No external links available for Setd1b.

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*Setd1b^{tm1(IMPC)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Setd1b^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell mouse
*Setd1b^{tm1.2(IMPC)Wtsi}*	Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette)	‌	mouse

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