Xylt1 | xylosyltransferase 1

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Pigmentation Integument Growth/size/body region Limbs/digits/tail Behavior/neurological Mortality/aging Craniofacial

12 No significant impact

5 Not tested

Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsXylt1em1(IMPC)JheterozygoteEarly adult8.92x10-5 
abnormal facial morphology1 supporting datasetXylt1em1(IMPC)JhomozygoteE18.5N/A * 
abnormal vocalization1 supporting datasetXylt1em1(IMPC)JheterozygoteEarly adult2.94x10-10 
abnormal limb morphology1 supporting datasetXylt1em1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetXylt1em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal behavior1 supporting datasetXylt1em1(IMPC)JheterozygoteEarly adult8.92x10-5 
abnormal coat/hair pigmentation1 supporting datasetXylt1em1(IMPC)JheterozygoteEarly adult4.2x10-12 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Xylt1em1(IMPC)JExon Deletionmouse

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