Tspoap1 | TSPO associated protein 1
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Nervous system Behavior/neurological
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating alkaline phosphatase level | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Late adult | 9.3x10-8 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Early adult | 3.42x10-5 | ||
| decreased total body fat amount | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Late adult | 2.25x10-5 | ||
| decreased circulating total protein level | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Early adult | 6.06x10-5 | ||
| increased grip strength | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Late adult | 4.42x10-5 | ||
| decreased prepulse inhibition | 1 supporting dataset | Tspoap1em1(IMPC)H | homozygote | Early adult | 2.28x10-5 |
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Human diseases caused by Tspoap1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tspoap1.
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| Tspoap1em1(IMPC)H | Indel | | mouse |
| Tspoap1em2(IMPC)H | Indel | | mouse |
| Tspoap1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Tspoap1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Tspoap1tm65(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |