Adamts15 | ADAM metallopeptidase with thrombospondin type 1 motif 15

GeneMGI:2449569

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Hearing/vestibular/ear

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged epididymis	1 supporting dataset	Adamts15^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Adamts15^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Adamts15^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.9x10^-6
increased circulating insulin level	1 supporting dataset	Adamts15^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.99x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adamts15.

Associated images

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Histopathology

There is no histopathology data found for Adamts15.

IMPC related publications

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External links

No external links available for Adamts15.

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*Adamts15^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Adamts15^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Adamts15^{tm372470(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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