Gemin4 | gem nuclear organelle associated protein 4

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Behavior/neurological

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating total protein level1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult9.1x10-6 
abnormal motor capabilities/coordination/movement1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult4.17x10-5 
increased total body fat amount1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult4.09x10-5 
increased circulating HDL cholesterol level1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult1.45x10-5 
increased circulating alkaline phosphatase level1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult2.52x10-6 
increased circulating cholesterol level1 supporting datasetGemin4em1(IMPC)IcsheterozygoteEarly adult3.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Gemin4em1(IMPC)IcsDeletionmouse
Gemin4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Gemin4tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter