Gemin5 | gem nuclear organelle associated protein 5

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetGemin5em1(IMPC)HhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetGemin5em1(IMPC)HhomozygoteE9.5N/A * 
increased mean platelet volume1 supporting datasetGemin5em1(IMPC)HheterozygoteEarly adult3.02x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gemin5em1(IMPC)HExon Deletionmouse

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