Nbeal2 | neurobeachin-like 2
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Skeleton
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| thrombocytopenia | 1 supporting dataset | Nbeal2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.74x10-20 | ||
| decreased bone mineral density | 1 supporting dataset | Nbeal2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.59x10-6 | ||
| increased leukocyte cell number | 1 supporting dataset | Nbeal2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.63x10-10 | ||
| increased mean platelet volume | 1 supporting dataset | Nbeal2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.53x10-16 | ||
| decreased bone mineral content | 1 supporting dataset | Nbeal2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.61x10-5 |
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Human diseases caused by Nbeal2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Nbeal2.
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| Nbeal2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nbeal2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |