Mmgt2 | membrane magnesium transporter 2

GeneMGI:2448491

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Immune system Integument Hematopoietic system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



impaired glucose tolerance	1 supporting dataset	Mmgt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.66x10^-7
decreased lymphocyte cell number	1 supporting dataset	Mmgt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.87x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Mmgt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.15x10^-5
increased basophil cell number	1 supporting dataset	Mmgt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.46x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mmgt2.

Associated images

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Histopathology

There is no histopathology data found for Mmgt2.

IMPC related publications

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External links

No external links available for Mmgt2.

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*Mmgt2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mmgt2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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