H4c16 | H4 histone 16

GeneMGI:2448443Synonyms: B130044J01Rik, Hist4h4, +2 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged kidney	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal pancreas morphology	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	1.57x10^-8
enlarged thymus	1 supporting dataset	H4c16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H4c16.

Associated images

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Histopathology

There is no histopathology data found for H4c16.

IMPC related publications

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External links

No external links available for H4c16.

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*H4c16^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse

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