H4c16 | H4 histone 16
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system
14 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged kidney | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal pancreas morphology | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| anophthalmia | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | 1.57x10-8 | ||
| enlarged thymus | 1 supporting dataset | H4c16em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by H4c16 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for H4c16.
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| H4c16em1(IMPC)Mbp | Whole-gene deletion | | mouse |