Lrrc3 | leucine rich repeat containing 3

GeneMGI:2447899Synonyms: 1300011L04Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength2 supporting datasetsLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult7.88x10-6 
increased circulating calcium level1 supporting datasetLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult5.84x10-6 
decreased lymphocyte cell number1 supporting datasetLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult6.88x10-5 
increased body length1 supporting datasetLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult2.81x10-5 
increased circulating phosphate level1 supporting datasetLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult3.08x10-5 
hyperactivity1 supporting datasetLrrc3tm1b(EUCOMM)HmguhomozygoteEarly adult5.92x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrrc3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Lrrc3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Lrrc3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Lrrc3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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