Klk14 | kallikrein related-peptidase 14

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton Renal/urinary system

17 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
88Embryo tissues

Phenotypes

increased urine microalbumin level1 supporting datasetKlk14tm1.1(KOMP)VlcghomozygoteEarly adult9.75x10-5 
decreased circulating glucose level1 supporting datasetKlk14tm1.1(KOMP)VlcghomozygoteEarly adult5.2x10-5 
abnormal bone structure1 supporting datasetKlk14tm1.1(KOMP)VlcghomozygoteEarly adult8.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klk14tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Klk14tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Klk14tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Klk14tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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