Slc24a4 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Nervous system Hematopoietic system Mortality/aging
12 No significant impact
6 Not tested
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| enlarged thymus | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 2 supporting datasets | Slc24a4tm1b(KOMP)Wtsi | homozygote | Early adult | 3.81x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.62x10-6 | ||
| increased circulating fructosamine level | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.89x10-5 | ||
| decreased red blood cell distribution width | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.02x10-6 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | homozygote | Early adult | 2.11x10-8 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Slc24a4tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.77x10-6 |
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External links
No external links available for Slc24a4.
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| Slc24a4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Slc24a4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |