Prss50 | serine protease 50

GeneMGI:2447303Synonyms: Tsp50

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased CD8-positive, alpha-beta T cell number1 supporting datasetPrss50tm1a(EUCOMM)HmguhomozygoteEarly adult3.89x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prss50tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Prss50tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Prss50tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Prss50tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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