Fbxo2 | F-box protein 2

GeneMGI:2446216Synonyms: FBX2, Fbs1, +2 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased fasting circulating glucose level	1 supporting dataset	Fbxo2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.77x10^-5
decreased locomotor activity	2 supporting datasets	Fbxo2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.48x10^-5
increased circulating glucose level	1 supporting dataset	Fbxo2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.89x10^-11
decreased startle reflex	1 supporting dataset	Fbxo2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo2.

Associated images

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Histopathology

There is no histopathology data found for Fbxo2.

IMPC related publications

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External links

No external links available for Fbxo2.

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*Fbxo2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fbxo2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fbxo2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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