Sh2d5 | SH2 domain containing 5

GeneMGI:2446215

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating creatinine level	1 supporting dataset	Sh2d5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.06x10^-5
abnormal vertebral arch morphology	1 supporting dataset	Sh2d5^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sh2d5.

Associated images

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Histopathology

There is no histopathology data found for Sh2d5.

IMPC related publications

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External links

No external links available for Sh2d5.

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*Sh2d5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Sh2d5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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